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Comprehensive and flexible genome sequencer

DNBSEQ-G400 is built with a new Flow Cell system that can flexibly support a variety of different sequencing modes. It adopts optimized optical and biochemical systems, which can complete the sequencing process rapidly, providing users with a more streamlined sequencing experience.


55GB~1440GB per run

PE150(FCS) sequencing at full capacity in only 37 hours

Support a range of read lengths including SE50, SE100, SE400, PE100, PE150, PE200, PE300

Support sequencing and data analysis in a wide range of areas including basic research, clinical research, forensics, and agriculture.

Performance Parameter

DNBSEQ-G400 Specifications
Platform DNBSEQ-G400
Flow Cell No. 2
Flow Cell Type FCS FCL
Lane No./Flow Cell 2 4
Effective Reads/Flow Cell* 300M/550M 1500-1800M
Read Lengths
* The maximum number of effective reads are based on the sequencing of an internal standard library. Actual output may vary with sample types and library preparation methods.
DNBSEQ-G400RS Performance
Read Lengths Data Output/Flow Cell Data Quality Q30* Run Time**
SE50-FCL 75-90G >85% ~14hrs
SE100-FCL 150-180G >85% ~25hrs
SE400-FCL 600-720G >70% ~109hrs
PE100-FCL 300-360G >85% ~38/48h***
PE150-FCL 450-540G >80% ~56/66h***
PE200-FCL 600-720G >75% ~107hrs
SE100-FCS 55G >85% ~13hrs
PE100-FCS 110G >85% ~26hrs
PE150-FCS 165G >80% ~37hrs
PE300-FCS 180G >80% ~98hrs
* The percentage of base above Q30 is the average of an internal standard library over the entire run. The actual performance is affected by factors such as sample type, library quality, and insert fragment length.
** Run time is calculated based on dual-slide mode including sample loading, sequencing, base calling, and data processing.
***38h and 56h are the run time after upgrading the latest version

System Parameter

Operating Environment Requirements

Temperature: 19~25℃

Relative Humidity: 20% RH~80% RH, non-condensing

Atmospheric Pressure: 70kPa~106 kPa

Waterproof Rating: IPX0

Control Computer Configurations

CPU: Intel Xeon E5 10Core x 2  2.2GHz

Internal Storage: 256GB RAM
SSD: 480G
Operating System: Windows 10 Enterprise

Power & Dimensions & Net Weight

Power Type: 100V~240V,50/60Hz

Rated Power: 1200VA

Dimensions(L×W×H): 1086mm×756mm×710mm

Net Weight: 200kg

Product Model*


**DNBSEQ-G400RS (for research only)

**DNBSEQ-G400CX (clinical purpose, overseas IVD)

Remark: *means that “the product model names, DNBSEQ-G400 and  MGISEQ-2000, are used in the selected oversea countries and China, respectively.”  

**means that “*Unless otherwise informed, StandardMPS and CoolMPS sequencing reagents, and sequencers for use with such reagents are not available in Germany, USA, Spain, UK, Hong Kong, Sweden, Belgium, Italy, Finland, Czech Republic, Switzerland, Portugal and Austria.”  

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